范光耀

姓名：范光耀 博士，硕士生导师

职称职务：副教授、副主任法医师，医学院基础医学部专任教师

社会兼职：浙江省司法鉴定协会法医物证专业指导委员会副主任委员

研究方向：RNA编辑技术、法医遗传学、分子人类学

主讲课程：《病理学》、《高级病理生理学》、《人体形态学》、《法医学》、《PATHOLOGY》

发表代表性研究论文：

1. Jiarui Li, Guangyao Fan, Matomo Sakari, Toshifumi Tsukahara*. Improvement of C-to-U RNA editing using an artificial MS2-APOBEC system[J]. Biotechnol J, 19(1):e2300321 (2024). SCI

2. Jiarui Li, Tomoko Oonishi, Guangyao Fan, Matomo Sakari, Toshifumi Tsukahara*. Increasing the Editing Efficiency of the MS2-ADAR System for Site-Directed RNA Editing[J]. Appl Sci, 13(4):2383 (2023). SCI

3. Junling Mo, Guangyao Fan, Toshifumi Tsukahara*, Matomo Sakari. The Role of the Exonic lncRNA PRKDC-210 in Transcription Regulation[J]. Int J Mol Sci, 23(22):137832022 (2022). SCI (TOP)

4. Guangyao Fan*, Qian Zhao, et al. Developmental validation of a complementary Y-STR system for the amplification of forensic samples[J]. Forensic Sci Int, 346:111667 (2023).  SCI

5. Guangyao Fan*, Dezhi Jiang, et al. Phylogenetic analyses of 41 Y-STRs and machine learning-based haplogroup prediction in the Qingdao Han population from Shandong Province, Eastern China[J]. Ann Hum Biol, 50(1):35~41 (2023).  SCI & SSCI

6. Guangyao Fan*. Assessing the factors influencing the performance of machine learning for classifying haplogroups from Y-STR haplotypes[J]. Forensic Sci Int, 340: 111466 (2022).  SCI

7. Yang Liu, Yi Ye, Guangyao Fan*, et al. Phylogenetic analyses of the 19 STR loci in X chromosome revealed discriminant forensic characteristics for Chinese Daur and Oroqen minorities[J]. Int J Leg Med, 136:551~553 (2022) SCI (TOP)

8. Guangyao Fan*, Danlu Song, et al. Gene flow and phylogenetic analyses of paternal lineages in the Yi-Luo valley using Y-STR genetic markers [J]. Ann Hum Biol, 48(7-8):627~634 (2021).  SCI & SSCI

9. Guangyao Fan*, Danping Wang, et al. Developmental validation study of a 32-plex STR direct amplification system for forensic reference samples[J]. Forensic Sci Int, 327:110977 (2021).  SCI

10. Mengnan Liu, Changxiu Peng, Guangyao Fan*, et al. Y-STR Haplotypic Polymorphisms for the Hakka Population in West China and Phylogenic Comparison with Other Chinese Populations[J]. Human Biology, 93(4), 247~268 (2021). (preprint SCI+SSCI)

11. Yijun Zhou, Lei Huang, Haidong Liu, Mengnan Liu, Guangyao Fan*. Population genetic characteristics for populations on the Shandong Peninsula revealed by autosomal STR [J]. Ann Hum Biol, 48(2):157~159 (2021).  SCI & SSCI

12. Guangyao Fan*, Lipeng Pan, et al. Technical note: developmental validation of a novel 41-plex Y-STR system for the direct amplification of reference samples[J]. Int J Leg Med, 135, 409~419 (2021).  SCI (TOP)

13. Guangyao Fan*, Zhenqing Zhang, et al. Forensic and phylogenetic analyses of populations in the Tibetan-Yi corridor using 41 Y-STRs[J]. Int J Leg Med, 135, 783~785 (2021).  SCI

14. Guangyao Fan*, Yuran An, et al. Forensic and phylogenetic analyses among three Yi populations in Southwest China with 27 Y chromosomal STR loci[J]. Int J Leg Med, 133, 795~797 (2019).  SCI (TOP)

15. Guangyao Fan*, Yuran An, Yijun Zhou, et al. Phylogenic analysis and forensic genetic characterization of Guizhou Miao tribes from 58 microareas via autosomal STR[J]. Leg Med, 47: 101737 (2020).  SCI

16. Guangyao Fan*, Yuran An, Changxiu Peng, et al. Forensic and phylogenetic analyses among three Yi populations in Southwest China with 27 Y chromosomal STR loci[J]. Int J Leg Med, 133(3): 795~797 (2019).  SCI (TOP)

17. Yuzi Zheng, Yi Ye, Gang Cao, Guangyao Fan, et al. Genetic diversity and phylogenetic analyses of hui and Kazakh populations in northwest of China via 15 autosomal STR loci[J]. Forensic Sci Int: Genet Suppl Series, 7(1): 652~654 (2019) .

18. Guangyao Fan*, Wei Li, Yi Ye, et al. Haplotype diversity of 17 Y-chromosome STR loci in Han population from different areas of Sichuan Province, Southwest China[J]. Leg Med, 26: 73~75 (2017).  SCI

19. Michael Nothnagel*, Guangyao Fan, Fei Guo, et al. Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes[J]. Hum Genet, 136(5): 485~496 (2017).  SCI

20. Guangyao Fan*, Wei Li, Shengting Li, et al. An evaluation of the performance of DNA recovery from fired firearms and cartridge cases using microdialysis filtration[J]. Forensic Sci Int: Genet Suppl Series, 6: e246~e248 (2017).

21. Guangyao Fan, Yi Ye, Yiping Hou*. Detecting a hierarchical genetic population structure via Multi-InDel markers on the X chromosome[J]. Sci Rep, 6: 32178~32178 (2016). SCI

22. Guangyao Fan, Yi Ye, Haibo Luo, et al. Use of multi-InDels as novel markers to analyze 13 X-chromosome haplotype loci for forensic purposes[J]. Electrophoresis, 36(23): 2931~2938 (2015).  SCI

23. Yi Ye, Jingshang Gao, Guangyao Fan, et al. Population genetics for 23 Y-STR loci in Tibetan in China and confirmation of DYS448 null allele[J]. Forensic Sci Int Genet, 5, 16: e7~e10 (2015).  SCI (TOP)

24. Guangyao Fan, Yi Ye, Haibo Luo, et al. Screening of Multi-InDel markers on X-chromosome for forensic purpose[J]. Forensic Sci Int: Genet Suppl Series, 5:e42~e44 (2015) .

25. Guangyao Fan, Guisen Zhao, Yaonan Mo. Advances in Identification of Semen Stains[J]. National Journal of Andrology, 16(8):735~740 (2010).

    主持科研课题：

    1. 主持国家社科基金面上项目（21BMZ006）2021.07-2025.06 在研

    2. 国家留学基金管理委员会与日本北陆先端科学技术大学院大学合作项目（202108330112）2022.06-2023.06 结项

    3. 主持省高校重点实验室开放课题：基于四川人群 Y染色体谱系的新型姓氏宗族推断系统的研究与开发（2021YB01）2021.08-2023.07 结项

    4. 主持河南省科技厅省重点科技攻关项目：基于Multi-InDel新型遗传标记的族源推断系统及其在精准医学上的应用（172102310527）2017.01-2018.10 结项

    5. 主持省高校重点实验室开放课题：基于Multi-InDel新型遗传标记的四川汉族及藏族的人群分层研究（2016001）2016.04-2018.04 结项