周红，博士，助理研究员
主讲课程：《医学免疫学》、《医学检验科研设计》
研究方向：利用理论模拟计算，从事面向生命科学、医学、药学、材料等多学科交叉领域的理论研究工作。主要研究方向：肿瘤免疫领域的蛋白质互作、抗原肽优化设计，新型纳米药物的理性设计及其在阿尔茨海默病防治中的机理研究。
联系方式：hongzhou1589@163.com
研究成果：
在国际相关领域主流期刊发表SCI论文16篇，其中第一/共同第一作者9篇
[1] Zhou H, Yin X, Zhang G, Yang Z, Zhou R*. Advancing Nanomaterial-Based Strategies for Alzheimer’s Disease: A Perspective, JACS Au, 2025. (IF=8.6, 化学1区Top)
[2] Yin X#, Zhou H#, Cao T#, Yang X, Meng F, Dai X, Wang Y, Li S J, Zhai W, Yang Z*, Chen N*, Zhou R*. Rational Design of Dual-Functionalized Gd@C82 Nanoparticles to Relieve Neuronal Cytotoxicity in Alzheimer's Disease via Inhibition of Aβ Aggregation [J]. ACS nano, 2024, 18(24): 15416-15431. (IF=17.1, 材料科学1区Top, 共同第一作者)
[3] Yin X#, Zhou H#, Zhang M#, Su J, Wang X, Li S, Yang Z*, Kang Z*, Zhou R*. C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer's disease [J]. Nature Communications, 2023, 14(1): 5718. (IF=16.6, 综合性期刊1区Top, 共同第一作者)
[4] Zhou H, Chan K, Buratto D, Zhou R*. The rigidity of a structural bridge on HLA-I binding groove explains its differential outcome in cancer immune response [J]. International Journal of Biological Macromolecules, 2023: 127199. (IF=8.2, 化学1区Top)
[5] Zhu Q#, Zhou H#, Wu L, Lai Z, Geng D, Yang W, Zhang J, Fan Z, Qin W, Wang Y, Zhou R*, Yi W*. O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1 [J]. Nature Chemical Biology, 2022, 18(10): 1087-1095. (IF=14.8, 生物学1区Top, 共同第一作者)
[6] Zhou H, Li Y, Yang Y, Liu S, Yang Z*. Lanosterol reduces the aggregation propensity of ultraviolet-damaged human γD-crystallins: a molecular dynamics study [J]. Physical Chemistry Chemical Physics, 2021, 23(24): 13696-13704. (IF=3.945, 化学2区Top)
[7] Zhou H, Liu S, Yin X, Li Z, Yang Z, Zhou R. Molecular Origin of the Stability Difference in Four Shark IgNAR Constant Domains [J]. Biophysical Journal, 2019, 116(10): 1907-1917. (IF=3.854, 生物物理2区Top)
[8] Zhou H#, Yang Z#, Tian X#, Chen L, Lee S, Huynh T, Ge C*, Zhou R*. Lanosterol Disrupts the Aggregation of Amyloid-β Peptides [J]. ACS Chemical Neuroscience, 2019, 10(9): 4051-4060. (IF=4.486, 药物化学2区)
[9] Zhou H, Liu S, Shao Q, Ma D, Yang Z*, Zhou R*. Mechanism by which DHA inhibits the aggregation of KLVFFA peptides: A molecular dynamics study [J]. The Journal of Chemical Physics, 2018, 148(11): 115102. (IF=2.997, 物理2区Top)
[10] Xie X, Hou Z, Duan G, Zhang S, Zhou H, Yang Z, Zhou R*. Boron nitride nanosheets elicit significant hemolytic activity via destruction of red blood cell membranes [J]. Colloids and Surfaces B: Biointerfaces. 2021, 203, 111765. (IF=5.8)
[11] Ge X#, Dai X#, Zhou H, Yang Z, Zhou R*. Stabilization of Open-Shell Single Bonds within Endohedral Metallofullerene [J]. Inorganic Chemistry, 2020, 59(6): 3606-3618.
[12] Tang X#, Zhang S#, Zhou H, Zhou B, Liu S, Yang Z*. The role of electrostatic potential polarization in the translocation of graphene quantum dots across membranes [J]. Nanoscale. 2020, 12, 2732-2739. (IF=6.7)
[13] Liu S#, Yin X#, Zhou H, Zhou B, Shao Q, Yang Z*, Zhou R*. Different platinum crystal surfaces show very distinct protein denaturation capabilities [J]. Nanoscale. 2019, 11, 19352-19361. (IF=6.7)
[14] Yin X, Liu S, Perez-Aguilar J, Zhou H, Shao Q, Yang Z*, Zhou R*. Different protonated states at the C-terminal of the amyloid- peptide modulate the stability of S-shaped protofibril [J]. Journal of Chemical Physics, 2019, 150, 185102. (IF=4.4)
[15] Gu Z, Yang Z, Luan B, Zhou X, Hong L, Zhou H, Luo J, Zhou R*. Membrane Insertion and Phospholipids Extraction by Graphyne Nanosheets [J]. Journal of Physical Chemistry C, 2017, 121, 2444-2450. (IF=3.7)
[16] Gu Z, Yang Z, Wang L, Zhou H, Jimenez-Cruz C. A, Zhou R*. The role of basic residues in the adsorption of blood proteins onto the graphene surface [J]. Scientific Reports, 2015, 5, 10873. (IF=4.6)
主持或参与课题：
科技部，国家重点研发计划，2021YFF1200404，蛋白质结构预测算法研究及蛋白质设计应用—《分子动力学模拟和高精度结构修正研究》子课题，2021-12 至2024-11，参与
专利：
尹秀华，刘胜堂，周红，李友云，杨再兴，谌宁，周如鸿. (2019) 改性内嵌金属富勒烯及其制备方法与应用，公开号: CN110179822A.
