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陈明敏

发布者:管理员   发布日期:2014-06-06   浏览次数:

姓名:陈明敏

性别:女

学历:博士研究生

职称:讲师

职务:医学院国际交流与合作中心主任

研究方向:分子生理学

研究成果:

1.交通事故致弥漫性轴索损伤伤残等级鉴定89例分析,法医学杂志,2013296):437-439

2.Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3Cell Physiol Biochem2013,325):1386-402

3.TBL结合LBL模式在五年制临床医学专业医学心理学心理干预各论教学中的应用研究,中国保健营养,2013,235):807-808

4.生理学实验教学改革的探讨,中国中医药现代远程教育,2012107):66

5.SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation. J Clin Invest. 2012122(10):3629-34

6.The electroneutral Na:HCO₃⁻ cotransporter NBCn1 is a major pHi regulator in murine duodenum. J Physiol. 2012590(Pt 14):3317-33.

7.Recent advances in the molecular and functional characterization of acid/base and electrolyte transporters in the basolateral membranes of gastric and duodenal epithelial cells. Acta Physiol (Oxf). 2011201(1):3-20

8.Loss of PDZadaptor protein NHERF2 affects membrane localization and cGMPand [Ca2+] but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine. J Physiol (London)2010588(Pt 24):5049-63

9.Gene ablation for PEPT 1 in mice abolishes the effects of dipeptides on small intestinal fluid absorption, short-circuit current, and intracellular pH. Am J Physiol Gastrointest Liver Physiol20102991):G265-74

10.The switch of intestinal Slc26 exchangers from anion absorptive to HCO formula secretory mode is dependent on CFTR anion channel function. Am J Physiol Cell Physiol20102985):C1057-65

11.Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells. Mol Biol Cell, 2010, 21(1):73-86

12.Lysophosphatidic acid stimulates the intestinal brush border Na+/H+ exchanger 3 and fluid absorption via LPA5 and NHERF2. Gastroenterology, 2010, 138(2):649-58

13.The role of the NHERF family of PDZ scaffolding proteins in the regulation of salt and water transport. Ann N Y Acad Sci, 2009, 1165:249-60

14.Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension Exp Physiol, 2009, 94(2):175-9

15.Defective jejunal and colonic salt absorption and altered Na+/H+ exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice. Pflugers Arch-Eur J Physiol20094575):1079-91

16.Sodium and chloride absorptive defects in the small intestine in Slc 26a 6 null mice. Pflugers Arch-Eur J Physiol20084554):757-66

17.NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol (London)2008581Pt3):1235-46

18.Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice. Pflugers Arch-Eur J Physiol20074544):575-86

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